X0306 4 2021-03-10 0 0001756262 TransMedics Group, Inc. TMDX 0001430466 Hassanein Waleed H C/O TRANSMEDICS GROUP, INC. 200 MINUTEMAN ROAD ANDOVER MA 01810 1 1 0 0 President & CEO Common Stock 2021-03-10 4 M 0 35007 2.21 A 373850 D Common Stock 2021-03-10 4 S 0 33043 33.74 D 340807 D Common Stock 2021-03-10 4 S 0 1964 34.67 D 338843 D Stock Option (Right to Buy) 2.21 2021-03-10 4 M 0 35007 0.00 D 2027-06-22 Common Stock 35007 193075 D The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $33.50 to $34.49 inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. The price reported is a weighted average price. These shares were sold in multiple transactions ranging from $34.50 to $34.84 inclusive. The Reporting Person undertakes to provide to the Company, any security holder of the Company or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. The option vests at a rate of 2.0833% of the total number of shares each month until the option is fully vested on the fourth anniversary of the vesting commencement date, June 22, 2017. /s/ Stephen Gordon, Attorney-in-Fact 2021-03-11