License and Option Agreement - Additional Information (Details) - USD ($) $ in Thousands			1 Months Ended	12 Months Ended
	Jul. 22, 2024	Jun. 03, 2021	Aug. 31, 2024	Dec. 31, 2024
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Option fee			$ 150,000
Option additional fee	$ 25,000
Recognized revenue related to the option fee payment and expense reimbursement				$ 200
Akebia Research License Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Up front payment received		$ 3,000
Amendment Akebia Research License Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Up front payment received				1,250
Additional up front payment				500
Commercialization milestone payments				$ 558,500