Nature of Business (Details) - USD ($) $ / shares in Units, $ in Thousands					1 Months Ended	12 Months Ended
	Dec. 13, 2024	Jul. 22, 2024	Jul. 28, 2023	Sep. 03, 2020	Aug. 31, 2024	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2021	Mar. 31, 2023
Nature of Business
Option fee					$ 150,000
Option additional fee		$ 25,000
Cash consideration transferrred			$ 8,000
Operating expenses			$ 2,400			$ 5,628	$ 12,951
Equity investment in cash									$ 5,000
Preferred stock, par value (in dollars per share)						$ 0	$ 0
Cash commission of gross proceeds of sales of common stock, percentage				3.00%
Proceeds from stock purchase agreement						$ 0	$ 5,000
Common stock issued or sold under the ATM Offering							0
Public float				$ 75,000
Net Income (Loss)						(3,057)	(5,263)
Accumulated deficit						(267,492)	(264,417)
Issuance of common stock							$ 1,953
Cyclerion
Nature of Business
Up front payment received	$ 1,750					1,250
Additional up front payment						500
Akebia
Nature of Business
Additional milestone cash payment						$ 558,500
Up front payment received								$ 3,000
Series A Convertible Preferred Stock
Nature of Business
Preferred stock, shares issued									351,037
Preferred stock, par value (in dollars per share)									$ 8.68
Common Stock
Nature of Business
Common stock shares issued									225,000
Issuance of common stock equity private placement and ATM (in shares)							225,000
ATM Offering | Maximum | Jefferies LLC
Nature of Business
Issuance of common stock				$ 50,000
Tisento Therapeutics Holdings Inc
Nature of Business
Outstanding equity securities			10.00%