License Agreement - Additional Information (Detail) - USD ($) $ in Thousands		3 Months Ended		6 Months Ended
	Jun. 03, 2021	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues		$ 306	$ 3,000	$ 1,017	$ 3,062
Akebia Research License Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Up Front Payment Received	$ 3,000
Additional milestone cash payment	$ 12,000
Akbeia Supply Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenues		$ 100		$ 300