X0206 3 2020-07-29 0 0001755237 Cyclerion Therapeutics, Inc. CYCN 0001559706 Slate Path Capital LP 717 5TH AVENUE 16TH FL. NEW YORK NY 10022 0 0 1 0 0001820641 Greenspan David Gerald C/O SLATE PATH CAPITAL LP 717 FIFTH AVENUE, 16TH FLOOR NEW YORK NY 10022 0 0 1 0 Common Stock, no par value 6196063 I See footnote The securities to which this filing relates are held by Slate Path Master Fund LP (the "Master Fund"), a Cayman Islands exempted limited partnership. Slate Path Capital LP (the "Investment Manager"), a Delaware limited partnership acts as the investment manager of the Master Fund. Mr. David Greenspan serves as the managing member of Jades GP, LLC, a Delaware limited liability company and the general partner of the Investment Manager. The filing of this statement shall not be deemed an admission that either Reporting Person is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Act of 1934, as amended, or otherwise. Each of the Reporting Persons expressly disclaims beneficial ownership of the securities reported herein except to the extent of its pecuniary interest therein. The Power of Attorney dated as of July 31, 2020 executed by David Greenspan authorizing Jim Feeney to sign and file this form on his behalf is attached hereto as Exhibit 24.1 Slate Path Capital LP, By: Jades GP, LLC, its General Partner, By: /s/ John Metzner, its Chief Operating Officer 2020-08-10 David Greenspan, By: /s/ Jim Feeney as Attorney-in-Fact 2020-08-10