X0306 4 2021-12-22 0 0001650664 Editas Medicine, Inc. EDIT 0001755098 ROBERTSON MICHELLE C/O EDITAS MEDICINE, INC. 11 HURLEY ST. CAMBRIDGE MA 02141 0 1 0 0 Chief Financial Officer Common Stock 2021-12-22 4 A 0 4471 0 A 33206 D Reflects the acquisition, upon the achievement of a specified research and development milestone, of a portion of a performance-based restricted stock unit award originally granted on June 2, 2021. The shares subject to the restricted stock unit award remain subject to time-based vesting conditions and will vest on June 2, 2022, subject to continued service. /s/ Michelle Robertson 2021-12-23