X0306 4 2020-11-09 0 0001351288 GW PHARMACEUTICALS PLC GWPH 0001754129 Gover Justin D. SOVEREIGN HOUSE, VISION PARK, HISTON CAMBRIDGE X0 CB24 9BZ UNITED KINGDOM 1 1 0 0 Chief Executive Officer Ordinary Shares 2020-11-09 4 M 0 3600 0.0013 A 459653 D Ordinary Shares 2020-11-09 4 M 0 3600 0.0013 A 463253 D Ordinary Shares 2020-11-09 4 S 0 7200 10.00 D 456053 D Ordinary Shares 2020-11-12 4 M 0 22800 0.0013 A 478853 D Ordinary Shares 2020-11-12 4 M 0 13917 0.0013 A 492770 D Ordinary Shares 2020-11-12 4 M 0 27591 0.0013 A 520361 D Ordinary Shares 2020-11-12 4 S 0 64308 10.01 D 456053 D Stock Options 0.0013 2020-11-09 4 M 0 3600 0.00 D 2020-02-15 2021-03-15 Ordinary Shares 3600 26734 D Stock Options 0.0013 2020-11-09 4 M 0 3600 0.00 D 2020-01-06 2021-03-15 Ordinary Shares 3600 13917 D Stock Options 0.0013 2020-11-12 4 M 0 22800 0.00 D 2020-02-15 2021-03-15 Ordinary Shares 22800 3934 D Stock Options 0.0013 2020-11-12 4 M 0 13917 0.00 D 2020-01-06 2021-03-15 Ordinary Shares 13917 0 D Stock Options 0.0013 2020-11-12 4 M 0 27591 0.00 D 2020-01-06 2021-03-15 Ordinary Shares 27591 205977 D Exercise of stock options. Following the exercise, these shares were converted into American Depositary Shares ("ADS") of the Issuer. Each ADS represents twelve ordinary shares of the Issuer. Converted from British Pounds Sterling to U.S. Dollars using currency ratio of 1.00 British Pound Sterling = 1.32 U.S. Dollars as of November 9, 2020. The sales reported were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 12, 2020. Represented by ADSs. The price reported in Column 4 is a price per ordinary share converted from price per ADS. Converted from British Pounds Sterling to U.S. Dollars using currency ratio of 1.00 British Pound Sterling = 1.31 U.S. Dollars as of November 12, 2020. The price reported in Column 4 is a weighted average price per ordinary share ($120.1715 per ADS). These shares were sold in multiple transactions at prices ranging from $120.00 per ADS (or $10.00 per ordinary share) to $120.46 per ADS (or $10.04 per ordinary share), inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. /s/ Justin D. Gover 2020-11-12