Income Taxes (Tables)

12 Months Ended

Dec. 31, 2025

Income Tax Disclosure [Abstract]

Summary of Loss Before Provision for Income Taxes

Loss before provision for income taxes for the years ended December 31, 2025 and 2024 consisted of the following (in thousands):

	Year Ended December 31,
	2025			2024
Federal	$	(43,438	)	$	(69,167	)
Foreign		—			—
Loss before provision for income taxes	$	(43,438	)	$	(69,167	)

Schedule of Provision for Income Taxes

The provision for income taxes for the years ended December 31, 2025 and 2024 consisted of the following (in thousands):

	December 31,
	2025		2024
Current income tax (benefit) expense:
Federal	$	—	$	—
State		—		—
Foreign		—		—
Total current income tax benefit		—		—
Deferred income tax (benefit) expense:		—		—
Federal		—		—
State		—		—
Foreign		—		—
Total deferred income tax benefit		—		—
Total income tax expense (benefit):	$	—	$	—

Schedule of Reconciliation of Effective Tax Rate for Income Taxes

The reconciliation of the effective tax rate for income taxes from the federal statutory rate for the years ended December 31, 2025 and 2024 was as follows (in thousands):

	Year Ended December 31,
	2025					2024
Income tax computed at federal statutory rate	$	(9,122	)	21.0	%	$	(14,525	)	21.0	%
State taxes		—		0.0	%		—		0.0	%
Tax credits - research and development tax credits		375		-0.9	%		(378	)	0.5	%
Change in valuation allowance		8,545		-19.6	%		11,642		-16.8	%
Nontaxable or nondeductible items
Loss on extinguishment and on issuance of convertible promissory notes		—		0.0	%		3,571		-5.2	%
Other		202		-0.5	%		(310	)	0.5	%
Effective income tax rate	$	—		0.0	%	$	—		0.0	%

Schedule of Significant Components of Deferred Tax Assets and Liabilities

The following table presents significant components of the Company’s deferred tax assets and liabilities as of December 31, 2025 and 2024 (in thousands):

	December 31,
	2025			2024
Deferred tax assets:
Net operating loss carryforwards	$	24,990		$	7,360
Capitalized R&D expenditures		24,869			5,115
Research credits		1,851			2,226
Accrued expenses and reserves		1,561			1,472
Other		—			3
R&D funding arrangement		9,037			7,291
Total deferred tax assets		62,308			23,467
Less valuation allowance		(62,308	)		(23,467	)
Net deferred tax assets	$	—		$	—

Summary of Income Taxes Paid (Net of Refunds Received)

The following summarizes the Company's income taxes paid (net of refunds received) for the years ended December 31, 2025 and 2024 (in thousands):

	Year Ended December 31,
	2025		2024
Federal	$	—	$	—
State		—		—
Foreign		—		—
Total	$	—	$	—

Schedule of Reconciliation of Beginning and Ending Balances of Unrecognized Tax Benefits

A reconciliation of the beginning and ending balances of the unrecognized tax benefits during the years ended December 31, 2025 and 2024, is as follows (in thousands):

	Year Ended December 31,
	2025			2024
Beginning Balance	$	680		$	514
Increase (decrease) based on current year tax positions		—			166
Increase (decrease) for prior year tax positions		(125	)		—
Ending Balance	$	555		$	680