Income Taxes - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Income Taxes [Line Items]
Increase (decrease) in deferred tax assets valuation allowance	$ (24,396,000)	$ 98,714,000
Operating loss carryforwards carryback period	5 years
Percentage of TCJA limitations on net operating loss carryforwards to taxable income	80.00%
Uncertain tax positions	$ 0	0
Unrecognized tax benefits, interest and penalties accrued	$ 0	0
Open tax year	2021 2022 2023 2024
Net Operating Losses, Tax Credits
Income Taxes [Line Items]
Increase (decrease) in deferred tax assets valuation allowance		98,700,000
Federal
Income Taxes [Line Items]
Operating loss carryforwards	$ 354,700,000	38,900,000
Federal | Research and Development
Income Taxes [Line Items]
Tax credit carryforwards	$ 11,700,000	11,700,000
Tax credit carryforwards expiration year	2040
Federal | Orphan Drug Credit (ODC)
Income Taxes [Line Items]
Tax credit carryforwards	$ 6,000,000
Tax credit carryforwards expiration year	2041
State
Income Taxes [Line Items]
Operating loss carryforwards	$ 168,400,000	26,400,000
State | Research and Development
Income Taxes [Line Items]
Tax credit carryforwards	$ 2,100,000	2,100,000
Tax credit carryforwards expiration year	2035
Foreign
Income Taxes [Line Items]
Operating loss carryforwards	$ 123,900,000	$ 354,800,000