Stock-Based Compensation - Additional Information (Details) - USD ($)				1 Months Ended	12 Months Ended
	Dec. 19, 2024	Jan. 01, 2024	Jul. 02, 2020	Jul. 31, 2020	Dec. 31, 2024	Dec. 31, 2023	May 15, 2023
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Accelerated units					28,954
Accelerating recognition cost					$ 100,000
Reversal of stock-based compensation expense					$ 4,000,000
Reserved shares of common stock for issuance					1,016,128	798,136
Common stock, par value					$ 0.0001	$ 0.0001	$ 0.0001
Stock-based compensation expense					$ 26,347,000	$ 40,779,000
Restricted Common Stock
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized stock-based compensation cost					$ 2,500,000
Weighted average period of cost expected to be recognized					1 year 7 months 24 days
Total fair value of restricted stock vested					$ 1,200,000	$ 3,600,000
Employee Stock Option
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of options, granted					0
Weighted average period of cost expected to be recognized					1 year 7 months 17 days
Weighted average grant-date fair value of stock options granted						$ 112.24
Unrecognized stock-based compensation expenses					$ 2,900,000
Research and Development
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Reversal of stock-based compensation expense					2,400,000
Stock-based compensation expense					510,000	$ 13,167,000
General and Administrative
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Reversal of stock-based compensation expense					1,600,000
Stock-based compensation expense					$ 25,837,000	$ 27,612,000
General and Administrative | Brainard Separation Agreement
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation expense	$ 6,600,000
2020 Stock Option and Grant Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Awards vesting period			4 years
Awards contractual term			10 years
Common stock authorized for issuance			348,205
Cumulative increase in number shares reserved for issuance, percentage			5.00%
Shares added to number of available shares under plan		248,150
2020 Stock Option and Grant Plan | Stock Available For Grant
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Reserved shares of common stock for issuance					657,495	181,846
Common stock issuable upon exercise of outstanding options					657,495
2020 Employee Stock Purchase Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Reserved shares of common stock for issuance				26,580	68,924
Percentage of payroll deductions of base salary or wages				15.00%
Percentage of maximum discount on purchase of shares of common stock				15.00%
Offering period, description					(i) on the first trading day of the offering period or (ii) the last day of any offering period. The Company utilizes the Black Scholes option pricing model to compute the fair market value of the shares and compensation expense is recognized over the offering period. Six-month offering periods commence each January 1 and July 1 during the term of the plan, with the administrator having the right to establish different offering periods.
Cumulative increase in number shares reserved for issuance, percentage				1.00%
Shares added to number of available shares under plan		49,631
Common stock, par value				$ 0.0001
Annual increase in number of shares reserved for issuance				53,161
Purchase of common stock under the employee stock purchase plan					1,582
Share issued, average price per share					$ 13.34
Cash received from purchases under the ESPP					$ 0	$ 300,000
Stock-based compensation expense					$ 0	$ 300,000
2020 Employee Stock Purchase Plan | Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Base salary or wages				$ 25,000