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Nature of the Business - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Net losses attributable to common stockholders $ (41,183) $ (43,863)  
Accumulated deficit (506,958)   $ (465,775)
Cash, cash equivalents and short-term investments $ 202,600