Stock-Based Compensation - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Share-based Payment Arrangement [Abstract]
Number of Options Outstanding, Beginning Balance	6,155,055
Number of Options, Granted	1,764,190
Number of Options, Forfeited	(411,939)
Number of Options Outstanding, Ending Balance	7,507,306	6,155,055
Options vested and exercisable at March 31, 2022	1,709,930
Weighted Average Exercise Price, Options outstanding as of January 1, 2022	$ 23.42
Weighted Average Exercise Price, Granted	9.19
Weighted Average Exercise Price, Forfeited	25.10
Weighted Average Exercise Price, Options outstanding at March 31, 2022	19.98	$ 23.42
Weighted Average Exercise Price, Options vested and exercisable at March 31, 2022	$ 21.44
Weighted Average Contractual Life, Options outstanding	8 years 10 months 17 days	8 years 9 months 18 days
Weighted Average Contractual Life, Options vested and exercisable at March 31, 2022	8 years 4 months 28 days
Aggregate Intrinsic Value, Options outstanding at January 1, 2022	$ 480
Aggregate Intrinsic Value, Options outstanding at March 31, 2022	181	$ 480
Aggregate Intrinsic Value, Options vested and exercisable at March 31, 2022	$ 122