Accrued Expenses - Schedule of Accrued Expenses (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Employee compensation and benefits	$ 2,099	$ 6,867
Professional fees	642	738
Research and development	4,245	3,573
Process development and manufacturing costs	2,703	7,685
Other	394	1,289
Total accrued expenses	$ 10,083	$ 20,152