X0206 3 2018-09-20 0 0001661998 Homology Medicines, Inc. FIXX 0001754067 Kelly Timothy P C/O HOMOLOGY MEDICINES, INC. 45 WIGGINS AVENUE BEDFORD MA 01730 0 1 0 0 See Remarks Employee Stock Options 2.8947 2027-09-06 Common Stock 38001 D Employee Stock Option 6.6314 2027-12-06 Common Stock 47500 D Employee Stock Option 16.00 2028-03-26 Common Stock 95002 D The option vests and becomes exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was May 30, 2017. The option vests and becomes exercisable upon the Reporting Person's completion of each full month of service after January 1, 2018, so that such option will become fully vested on January 1, 2022. The option vests and becomes exercisable in 48 equal monthly installments on the first day of each calendar month following March 27, 2018. Chief Technical Operations Officer Exhibit 24 - Power of Attorney. /s/ Bradford Smith, Attorney-in-Fact for Timothy P. Kelly 2018-09-27