X0306 4 2021-08-20 0 0001468748 Kodiak Sciences Inc. KOD 0001754049 EHRLICH JASON 1200 PAGE MILL ROAD PALO ALTO CA 94304 0 1 0 0 See Remarks Common Stock 2021-08-20 4 M 0 5258 10.29 A 58491 D Common Stock 2021-08-20 4 S 0 404 88.1665 D 58087 D Common Stock 2021-08-20 4 S 0 510 89.0558 D 57577 D Common Stock 2021-08-20 4 S 0 542 90.6425 D 57035 D Common Stock 2021-08-20 4 S 0 3193 91.5952 D 53842 D Common Stock 2021-08-20 4 S 0 2278 92.5218 D 51564 D Common Stock 2021-08-20 4 S 0 23 93.04 D 51541 D Stock Option (Right to Buy) 10.29 2021-08-20 4 M 0 5258 0.00 D 2028-08-29 Common Stock 5258 253288 D The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $87.66 to $88.40, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in these footnotes. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $88.81 to $89.78, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $89.945 to $90.94, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $91.10 to $91.995, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $92.02 to $92.995, inclusive. Twenty-five percent of the shares subject to the option vested on September 1, 2019, and 1/48th of the shares subject to the option vest on the same day of each month thereafter. Chief Medical Officer and Chief Development Officer /s/ David Peinsipp, Attorney-in-Fact for Jason Ehrlich 2021-08-24