X0306 4 2021-01-20 0 0001468748 Kodiak Sciences Inc. KOD 0001754049 EHRLICH JASON 2631 HANOVER STREET PALO ALTO CA 94304 0 1 0 0 See Remarks Common Stock 2021-01-20 4 M 0 26950 10.29 A 77293 D Common Stock 2021-01-20 4 S 0 6668 159.955 D 70625 D Common Stock 2021-01-20 4 S 0 4204 161.0281 D 66421 D Common Stock 2021-01-20 4 S 0 4956 162.0549 D 61465 D Common Stock 2021-01-20 4 S 0 2061 163.0952 D 59404 D Common Stock 2021-01-20 4 S 0 1497 164.507 D 57907 D Common Stock 2021-01-20 4 S 0 3132 165.6387 D 64775 D Common Stock 2021-01-20 4 S 0 3097 166.5136 D 51678 D Common Stock 2021-01-20 4 S 0 1335 167.1987 D 50343 D Stock Option (Right to Buy) 10.29 2021-01-20 4 M 0 26950 0.00 D 2028-08-29 Common Stock 26950 297275 D The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $159.51 to $160.45, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in these footnotes. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $160.56 to $161.51, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $161.70 to $162.65, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $162.75 to $163.68, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $164.03 to $164.91, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $165.11 to $166.04, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $166.12 to $167.00, inclusive. The price reported in Column 4 is a weighted-average price. The shares were sold in multiple transactions ranging from $167.14 to $167.68, inclusive. Twenty-five percent of the shares subject to the option vested on September 1, 2019 and 1/48th of the shares subject to the option vest on the same day of each month thereafter. Chief Medical Officer and Chief Development Officer /s/ Carlton Fleming, Attorney-in-Fact for Jason Ehrlich 2021-01-22