X0306 4 2019-05-23 0 0001655759 ARVINAS, INC. ARVN 0001753859 Kennedy Edward Moore Jr. C/O ARVINAS, INC. 5 SCIENCE PARK, 395 WINCHESTER AVE. NEW HAVEN CT 06511 1 0 0 0 Stock Option (right to buy) 22.06 2019-05-23 4 A 0 12923 0.00 A 2029-05-22 Common Stock 12923 12923 D This option award was granted on May 23, 2019. The shares underlying the award shall vest in full on May 23, 2020 or, if earlier, the date of the first meeting of the board of directors of the Issuer held after the Issuer's next annual meeting of stockholders. /s/ Matthew Batters, as attorney-in-fact for Edward Moore Kennedy, Jr. 2019-05-28