X0306 4 2021-10-13 0001581280 Twist Bioscience Corp TWST 0001753670 Banyai William C/O TWIST BIOSCIENCE CORPORATION 681 GATEWAY BLVD. SOUTH SAN FRANCISCO CA 94080 true true false false See Remarks Common Stock 2021-10-13 4 M false 16833 5.95 A 315109 D Common Stock 2021-10-13 4 M false 11348 8.82 A 326457 D Employee Stock Option (right to buy) 5.95 2021-10-13 4 M false 16833 0 A 2025-09-28 Common Stock 16833 84166 D Employee Stock Option (right to buy) 8.82 2021-10-13 4 M false 11348 0 A 2027-09-28 Common Stock 11348 141161 D The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversarythereafter, subject to the Reporting Person's continuous service through each vesting date. The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date. Senior Vice President of Advanced Development and General Manager of Data Storage /s/ William Solis, as Attorney-in-Fact for William Banyai 2021-10-15