X0306 4 2020-09-04 0001581280 Twist Bioscience Corp TWST 0001753655 Leproust Emily M. C/O TWIST BIOSCIENCE CORPORATION 681 GATEWAY BLVD. SOUTH SAN FRANCISCO CA 94080 true true false false President & CEO Common Stock 2020-09-04 4 S false 8309 60.9699 D 699389 D Common Stock 2020-09-04 4 S false 18491 61.8995 D 680898 D Common Stock 2020-09-04 4 S false 32890 63.1154 D 648008 D Common Stock 2020-09-04 4 S false 30147 63.8685 D 617861 D Common Stock 2020-09-04 4 S false 4405 64.7516 D 613456 D Common Stock 2020-09-04 4 S false 1876 65.9684 D 611580 D Common Stock 2020-09-04 4 S false 400 66.6875 D 611180 D Common Stock 2020-09-08 4 S false 3482 60.3549 D 607698 D Represents the weighted average sales price per share. The shares sold at prices ranging from $60.48 to $61.43 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $61.47 to $62.45 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $62.46 to $63.455 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $63.46 to $64.455 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $64.49 to $65.41 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $65.50 to $66.39 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $66.56 to $66.81 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. Represents the weighted average sales price per share. The shares sold at prices ranging from $60.10 to $60.72 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer. /s/ William Solis, as Attorney-in-Fact for Emily M. Leproust 2020-09-09