X0508 4 2025-03-04 0000004962 AMERICAN EXPRESS CO AXP 0001753557 Marrs Anna 200 VESEY STREET, AMERICAN EXPRESS TOWER NEW YORK NY 10285-5001 1 Group Pres., GMNS 1 Common Stock 2025-03-04 4 M 0 16274 177.06 A 47715.534 D Common Stock 2025-03-04 4 S 0 3677 285.00 D 44038.534 D Common Stock 2025-03-04 4 S 0 697 285.51 D 43341.534 D Common Stock 2025-03-04 4 S 0 2300 286.68 D 41041.534 D Common Stock 2025-03-04 4 S 0 8999 287.18 D 32042.534 D Common Stock 2025-03-04 4 S 0 301 287.78 D 31741.534 D Common Stock 2025-03-04 4 S 0 300 290.76 D 31441.534 D Common Stock 2025-03-04 4 S 0 5681 291.50 D 25760.534 D Employee Stock Option (Right to Buy) 177.06 2025-03-04 4 M 0 16274 0 D 2025-01-28 2032-01-28 Common Stock 16274 0 D The transactions reported on this Form 4 were effected pursuant to a 10b5-1 Trading Plan adopted by the reporting person on December 3, 2024. Includes shares acquired pursuant to dividend reinvestment. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $284.51 to $285.29. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $285.30 to $285.60. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $286.30 to $286.94. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $286.96 to $287.42. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $287.43 to $288.35. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $290.48 to $291.33. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. /s/ Douglas C. Turnbull, attorney-in-fact 2025-03-06