X0306 4 2023-02-14 0000004962 AMERICAN EXPRESS CO AXP 0001753557 Marrs Anna 200 VESEY STREET, AMERICAN EXPRESS TOWER NEW YORK NY 10285-5001 1 Group Pres., GCS and CFR Common Stock 2023-02-14 4 M 0 30971 131.68 A 59683.719 D Common Stock 2023-02-14 4 S 0 30261 179.19 D 29422.719 D Common Stock 2023-02-14 4 S 0 13400 180.19 D 16022.719 D Employee Stock Option (Right to Buy) 131.68 2023-02-14 4 M 0 30971 0 D 2023-01-29 2030-01-29 Common Stock 30971 0 D The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $178.89 to $179.885. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $179.90 to $180.79. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. Includes shares acquired pursuant to dividend reinvestment. /s/ Kristina V. Fink, attorney-in-fact 2023-02-16