144 0001752968 XXXXXXXX LIVE 0001576280 Guardant Health, Inc. 001-38683 3100 HANOVER STREET PALO ALTO CA 94304 855-698-8887 Eltoukhy Helmy Officer Common Stock Stifel Nicolaus & Company Inc

501 N Broadway St. Louis MO 63102

100000 12629970.00 132599929 06/05/2026 Nasdaq Common Stock 03/12/2025 Restricted Stock Units Issuer N 2374 03/12/2025 Equity Compensation Common Stock 03/31/2025 Restricted Stock Units Issuer N 9612 03/31/2025 Equity Compensation Common Stock 04/01/2025 Restricted Stock Units Issuer N 11835 04/01/2025 Equity Compensation Common Stock 06/30/2025 Restricted Stock Units Issuer N 2374 06/30/2025 Equity Compensation Common Stock 07/01/2025 Restricted Stock Units Issuer N 11835 07/01/2025 Equity Compensation Common Stock 09/30/2025 Restricted Stock Units Issuer N 2374 09/30/2025 Equity Compensation Common Stock 10/01/2025 Restricted Stock Units Issuer N 11835 10/01/2025 Equity Compensation Common Stock 12/31/2025 Restricted Stock Units Issuer N 2374 12/31/2025 Equity Compensation Common Stock 01/01/2026 Restricted Stock Units Issuer N 32090 01/01/2026 Equity Compensation Common Stock 03/13/2026 Restricted Stock Units Issuer N 13297 03/13/2026 Equity Compensation Y 06/05/2026 /s/ Brian Schneiweiss, as a duly authorized representative of STIFEL, as attorney-in-fact for Helmy Eltoukhy