X0306 4 2022-11-15 0 0001253176 VAPOTHERM INC VAPO 0001752887 Ramade Gregoire 100 DOMAIN DRIVE EXETER NH 03833 0 1 0 0 SVP & Chief Commercial Officer Common Stock 2022-11-15 4 P 0 10000 0.5399 A 83114 D Includes 59,900 shares that will be issued over time upon vesting and settlement of restricted stock units granted under the Vapotherm, Inc. Amended and Restated 2018 Equity Plan and the Vapotherm, Inc. Amended and Restated 2019 French Qualifying Sub Plan. /s/ Adrain Bryant, as Attorney In Fact 2022-11-17