X0306 4 2022-05-10 0 0001253176 VAPOTHERM INC VAPO 0001752887 Ramade Gregoire 100 DOMAIN DRIVE EXETER NH 03833 0 1 0 0 SVP and Chief Comm Officer Common Stock 33114 D Stock Option (right to buy) 3.16 2022-05-10 4 A 0 53000 0 A 2032-05-10 Common Stock 53000 53000 D Includes 19,900 shares that will be issued over time upon vesting and settlement of restricted stock units granted under the Vapotherm, Inc. 2018 Equity Incentive Plan (as amended from time to time, the "2018 Equity Plan") and the Vapotherm, Inc. Amended and Restated 2019 French Qualifying Sub Plan (the "French Sub Plan"). This option was granted under the 2018 Equity Plan and the French Sub Plan and will vest as to 25% of the underlying shares on January 1, 2024, and thereafter, as to the remaining 75% of underlying shares, in 36 monthly installments, subject to the reporting person's continued service as an employee or other service provider to the Issuer through the vesting dates. /s/Adrain Bryant, as Attorney In Fact 2022-05-12