X0306 4 2021-01-20 0 0001253176 VAPOTHERM INC VAPO 0001752887 Ramade Gregoire 100 DOMAIN DRIVE EXETER NH 03833 0 1 0 0 SVP & Chief Commercial Officer Common Stock 20614 D Employee Stock Option (right to buy) 12.16 2021-01-20 4 J 0 11375 0 A 2030-01-01 Common Stock 11375 11375 D Includes 9,900 shares that will be issued over time upon vesting pursuant to restricted stock units granted under the Vapotherm, Inc. 2018 Equity Incentive Plan. On January 1, 2020, the Reporting Person was granted a performance-based option under the Vapotherm, Inc. 2018 Equity Incentive Plan, the actual number of underlying shares of which was not ascertainable until determined by the Issuer's Compensation Committee after completion of the one-year performance period based on the Issuer's achievement of certain pre-determined performance goals for the year ended December 31, 2020. Once vested based on performance, the stock option would then be subject to additional time-based vesting. On January 20, 2021, the Issuer's Compensation Committee determined based on 2020 performance that the performance goals were achieved at a 100% level, resulting in an option to purchase a total of 11,375 shares for the Reporting Person, with the first 25% tranche vesting on that day and the remaining 75% to vest in 36 nearly equal monthly installments thereafter, provided the Reporting Person continues to serve as an employee or other service provider to the Issuer through the applicable vesting date. /s/Adrain Bryant, as Attorney In Fact 2021-04-27