<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2019-02-07</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001752836</issuerCik>
        <issuerName>COVETRUS, INC.</issuerName>
        <issuerTradingSymbol>CVET</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001765146</rptOwnerCik>
            <rptOwnerName>Cooke Russell</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>7 CUSTOM HOUSE STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>PORTLAND</rptOwnerCity>
            <rptOwnerState>ME</rptOwnerState>
            <rptOwnerZipCode>04101</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>331</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Received in the pro rata distribution of shares of common stock of Covetrus, Inc. (&quot;Covetrus&quot;) owned by Henry Schein, Inc. (&quot;Henry Schein&quot;) to the stockholders of Henry Schein in connection with the spin-off of the Henry Schein Animal Health Business into Covetrus, pursuant to the Contribution and Distribution Agreement, dated as of April 20, 2018, as amended, by and among Henry Schein, Covetrus, Direct Vet Marketing, Inc. (d/b/a Vets First Choice) (&quot;Vets First Choice&quot;), and Shareholder Representative Services LLC, solely in its capacity as the representative of the Vets First Choice stockholders and for the purposes of certain articles set forth therein.</footnote>
    </footnotes>

    <remarks>Exhibit List

Exhibit 24 - Power of Attorney

Senior Vice President and Operational Chief Financial Officer</remarks>

    <ownerSignature>
        <signatureName>/s/ Erin Powers Brennan, as attorney-in-fact for Russell Cooke</signatureName>
        <signatureDate>2019-02-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
