Schedule of Stock Option Activity (Details) - 2021 and 2017 Equity Incentive Plan [Member] - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2024		Dec. 31, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Options beginning balance	2,820,187
Weighted Average Exercise Price, beginning balance	$ 40.16
Weighted Average Contract Term	6 years 4 months 24 days	[1]	5 years 7 months 6 days
Aggregate Intrinsic Value
Options Granted	1,503,394
Weighted Average Exercise Price, Granted	$ 3.26
Options Exercised	(20,744)
Weighted Average Exercise Price, Exercised	$ 2.80
Options Forfeited/Expired	(341,312)
Weighted Average Exercise Price, Forfeited/Expired	$ 29.51
Options ending balance	3,961,525	[1]	2,820,187
Weighted Average Exercise Price, ending balance	$ 27.27	[1]	$ 40.16
Aggregate Intrinsic Value	$ 16	[1]
Options Vested and expected to vest	3,961,525
Weighted Average Exercise Price, Vested and expected to vest	$ 27.27
Weighted Average Contract Term, Vested and expected to vest	6 years 4 months 24 days
Aggregate Intrinsic Value Vested and expected to vest	$ 16
Options Exercisable	2,586,561
Weighted Average Exercise Price, Exercisable	$ 37.49
Weighted Average Contract Term Exercisable	4 years 10 months 24 days
Aggregate Intrinsic Value Exercisable

[1] Options outstanding at December 31, 2024 under the 2021 Plan and 2017 Plan were 2,569,029 and 1,437,496, respectively. Options outstanding at December 31, 2024 under the 2021 Plan include 45,000 awards with performance conditions (see below).