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License and Distribution Agreements - Additional Information (Details) - USD ($)
3 Months Ended 12 Months Ended
Sep. 01, 2021
May 07, 2021
Aug. 06, 2020
Apr. 03, 2020
Mar. 31, 2022
Dec. 31, 2021
License And Distribution Agreements [Line Items]            
Incentive payment         $ 0 $ 0
Reimbursement for enrolled patients in related clinical studies       $ 75,000    
Sanuwave License Agreement            
License And Distribution Agreements [Line Items]            
Licensing arrangement term     5 years      
License agreement, description           (i) its affiliates without the consent of the Company and (ii) any third party for the sole purpose of providing services directly to Sanuwave upon prior written consent by the Company. The Sanuwave License Agreement will automatically renew for additional one-year periods unless either party gives written notice of termination at least 180 days prior to the expiration of the then-current term. Under the Sanuwave License Agreement, the Company will receive a quarterly license fee and a defined royalty on each product sold. A credit is provided to Sanuwave for Biovance royalties up to the quarterly license fee amount.
Annual sales     $ 3,000,000      
Annual sales not exceed     $ 5,000,000      
Arthrex Agreement            
License And Distribution Agreements [Line Items]            
Supply and distribution agreement period   6 years        
Supply and distribution agreement renewal term   2 years        
Supply and distribution agreement non-renewal notice period   12 months        
Discount percentage, payment for invoices within ten days   2.00%        
Payment term, net   45 days        
Material breach, contract terminated term   30 days        
Evolution Agreement            
License And Distribution Agreements [Line Items]            
Supply and distribution agreement period 3 years          
Supply and distribution agreement renewal term 2 years          
Supply and distribution agreement non-renewal notice period 12 months          
Discount percentage, payment for invoices within ten days 2.00%          
Payment term, net 45 days          
Material breach, contract terminated term 30 days          
Percentage of payment upon receipt and acceptance of purchase order 50.00%          
Remaining due percentage, net forty five payment term 50.00%          
Supply and distribution agreement, forecast description The forecast may not deviate to less than 70% for the immediate following quarter, 50% two quarters out, 40% three quarters out, and 25% for full quarters from the original forecasted amount for that specific quarter set forth in the respective agreed upon binding forecast. Upon agreement, Evolution shall submit to the Company a purchase order to purchase products for the minimum binding forecasted quantities.         The forecast may not deviate to less than 70% for the immediate following quarter, 50% two quarters out, 40% three quarters out, and 25% for full quarters from the original forecasted amount for that specific quarter set forth in the respective agreed upon binding forecast. Upon agreement, Evolution shall submit to the Company a purchase order to purchase products for the minimum binding forecasted quantities.