Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	PIPE Investors	Registered Direct Offering	Pulthera Llc	CV Star Loan	Cumulative Effect, Period of Adoption, Adjustment	Common Stock	Common Stock PIPE Investors	Common Stock Registered Direct Offering	Common Stock Pulthera Llc	Additional Paid-in Capital	Additional Paid-in Capital PIPE Investors	Additional Paid-in Capital Registered Direct Offering	Additional Paid-in Capital Pulthera Llc	Additional Paid-in Capital CV Star Loan	Accumulated Deficit	Accumulated Deficit Cumulative Effect, Period of Adoption, Adjustment	Accumulated Other Comprehensive Income
Balance at Dec. 31, 2021	$ 99,418						$ 12				$ 763,087					$ (663,681)
Balance (Accounting Standards Update 2016-02) at Dec. 31, 2021						$ 3,993											$ 3,993
Balance (in Shares) at Dec. 31, 2021							12,430,788
Reclassification of previously exercised stock options	441										441
Reclassification of previously exercised stock options, in shares							13,125
Exercise of stock options	948										948
Exercise of stock options (in Shares)							171,047
Purchase and retirement of common shares	(86)										(86)
Purchase and retirement of common shares, in shares							(1,050)
Exercise of warrants	46,491						$ 2				46,489
Exercise of warrants, in shares							1,328,189
Common stock issued pursuant to short-term debt conversion	4,088						$ 1				4,098							$ (11)
Common stock issued pursuant to short-term debt conversion, in shares							262,797
Vesting of restricted stock units, in shares							23,252
Vesting of restricted stock units	0
Tax withholding on vesting of restricted stock units	(132)										(132)
Tax withholding on vesting of restricted stock units, in shares							(7,067)
Stock-based compensation expense	15,856										15,856
Issuance of common stock	6,021	$ 7,651									6,021	$ 7,651
Issuance of common stock (in Shares)							265,641	405,406
Change in fair value of debt due to change in credit risk, net of tax	20																	20
Net income (loss)	14,192															14,192
Balance at Dec. 31, 2022	198,901						$ 15				844,373					(645,496)		9
Balance (in Shares) at Dec. 31, 2022							14,892,129
Fair value of warrant modification for professional services	403										403
Common stock issued pursuant to short-term debt maturity extension, shares							270,731
Common stock issued pursuant to short-term debt maturity extension	712										712
Exercise of stock options	304										304
Exercise of stock options (in Shares)							108,637
Common stock issued pursuant to short-term debt conversion	4,444						$ 1				4,598							(155)
Common stock issued pursuant to short-term debt conversion, in shares							559,481
Vesting of restricted stock units, in shares							83,759
Vesting of restricted stock units	0
Tax withholding on vesting of restricted stock units	(101)										(101)
Tax withholding on vesting of restricted stock units, in shares							(19,130)
Stock-based compensation expense	15,017										15,017
Issuance of warrants	2,016				$ 274						2,016				$ 274
Issuance of common stock	136	$ 12,681	$ 1,322	$ 1,000				$ 1	$ 2		136	$ 12,680	$ 1,320	$ 1,000
Issuance of common stock (in Shares)							13,296	1,519,579	1,780,220	169,492
Change in fair value of debt due to change in credit risk, net of tax	146																	146
Net income (loss)	(196,295)															(196,295)
Balance at Dec. 31, 2023	$ 40,960						$ 19				$ 882,732					$ (841,791)		$ 0
Balance (in Shares) at Dec. 31, 2023							19,378,192