Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Cumulative Effect, Period of Adoption, Adjustment	Pulthera LLC	Private Investment in Public Equity Financing	Common Stock	Common Stock Pulthera LLC	Common Stock Private Investment in Public Equity Financing	Additional Paid-in Capital	Additional Paid-in Capital Pulthera LLC	Additional Paid-in Capital Private Investment in Public Equity Financing	Accumulated Deficit	Accumulated Deficit Cumulative Effect, Period of Adoption, Adjustment	Accumulated Other Comprehensive Income (Loss)
Balance at Dec. 31, 2021	$ 99,418				$ 12			$ 763,087			$ (663,681)
Balance (Accounting Standards Update 2016-02) at Dec. 31, 2021		$ 3,996										$ 3,996
Balance (in Shares) at Dec. 31, 2021					124,307,884
Reclassification of previously exercised stock options	441							441
Reclassification of previously exercised stock options, in shares					131,253
Exercise of warrants	46,485				$ 2			46,483
Exercise of warrants, in shares					13,281,386
Exercise of stock options	21							21
Exercise of stock options (in Shares)					10,255
Purchase and retirement of common shares					(3,058)
Purchase and retirement of common shares, value	(11)							(11)
Stock-based compensation expense	2,422							2,422
Net loss	(62,867)										(62,867)
Balance at Mar. 31, 2022	89,905				$ 14			812,443			(722,552)
Balance (in Shares) at Mar. 31, 2022					137,727,720
Balance at Dec. 31, 2022	198,901				$ 15			844,373			(645,496)		$ 9
Balance (in Shares) at Dec. 31, 2022					148,921,287
Exercise of stock options	300							300
Exercise of stock options (in Shares)					1,071,000
Common stock issued pursuant to short-term debt conversion	3,358				$ 1			3,509					(152)
Common stock issued pursuant to short-term debt conversion, in shares					3,656,118
Issuance of common stock (in Shares)					132,958	1,694,915	9,381,841
Issuance of common stock	136		$ 1,000	$ 8,931			$ 1	136	$ 1,000	$ 8,930
Vesting of restricted stock units, in shares					253,390
Tax withholding on vesting of restricted stock units, in shares					(81,095)
Tax withholding on vesting of restricted stock units	(53)							(53)
Issuance of warrants on senior secured bridge loan	274							274
Stock-based compensation expense	3,988							3,988
Change in fair value of debt due to change in credit risk, net of tax	2,810												2,810
Net loss	(64,017)										(64,017)
Balance at Mar. 31, 2023	$ 155,628				$ 17			$ 862,457			$ (709,513)		$ 2,667
Balance (in Shares) at Mar. 31, 2023					165,030,414