X0306 4 2021-06-04 0 0001396814 Pacira BioSciences, Inc. PCRX 0001752004 McLoughlin Dennis C/O PACIRA BIOSCIENCES, INC. 5 SYLVAN WAY, SUITE 300 PARSIPPANY NJ 07054 0 1 0 0 Chief Customer Officer Common Stock 2021-06-04 4 S 0 1895 61.037 D 27541 D Represents shares sold by the reporting person to cover tax obligations upon the vesting of restricted stock units. Includes 355 and 183 shares of common stock acquired under the issuer's employee stock purchase plan in June 2020 and December 2020, respectively. /s/ Kristen Williams, Attorney-in-Fact 2021-06-08