X0306 4 2022-08-09 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001751790 Wolff Stefani C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 0 1 0 0 EVP and COO Employee Stock Option (right to buy) 18.50 2022-08-09 4 A 0 110375 0.00 A 2032-08-08 Common Stock 110375 110375 D The stock option vests as to 1/48 of the total shares monthly beginning September 9, 2022 until the option is fully vested on August 9, 2026, subject to the Reporting Person's provision of service to the Issuer on each vesting date. /s/ Christine Ring, as Attorney-in-Fact for Stefani Wolff 2022-08-10