<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0001750821</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000070728</seriesId>
        <classId>C000224836</classId>
        <classId>C000224837</classId>
        <classId>C000224838</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
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    <genInfo>
      <regName>North Square Investments Trust</regName>
      <regFileNumber>811-23373</regFileNumber>
      <regCik>0001750821</regCik>
      <regLei>549300K2CKCXH4E67T58</regLei>
      <regStreet1>10 South LaSalle Street</regStreet1>
      <regStreet2>Suite 1925</regStreet2>
      <regCity>Chicago</regCity>
      <regStateConditional regCountry="US" regState="US-IL"/>
      <regZipOrPostalCode>60603</regZipOrPostalCode>
      <regPhone>3128572160</regPhone>
      <seriesName>North Square Tactical Growth Fund</seriesName>
      <seriesId>S000070728</seriesId>
      <seriesLei>549300RLZ8OFZAGS4U90</seriesLei>
      <repPdEnd>2023-05-31</repPdEnd>
      <repPdDate>2023-02-28</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>468453424.650000000000</totAssets>
      <totLiabs>910720.200000000000</totLiabs>
      <netAssets>467542704.450000000000</netAssets>
      <assetsAttrMiscSec>0.000000000000</assetsAttrMiscSec>
      <assetsInvested>0.000000000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.000000000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.000000000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.000000000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.000000000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.000000000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.000000000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.000000000000</amtPayAftOneYrOther>
      <delayDeliv>0.000000000000</delayDeliv>
      <standByCommit>0.000000000000</standByCommit>
      <liquidPref>0.000000000000</liquidPref>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000224836" rtn1="-4.160000000000" rtn2="4.540000000000" rtn3="-2.120000000000"/>
          <monthlyTotReturn classId="C000224837" rtn1="-4.080000000000" rtn2="4.630000000000" rtn3="-2.040000000000"/>
          <monthlyTotReturn classId="C000224838" rtn1="-4.100000000000" rtn2="4.600000000000" rtn3="-2.060000000000"/>
        </monthlyTotReturns>
        <othMon1 netRealizedGain="-1426179.550000000000" netUnrealizedAppr="-19879890.430000000000"/>
        <othMon2 netRealizedGain=".000000000000" netUnrealizedAppr="21302027.370000000000"/>
        <othMon3 netRealizedGain="126085.470000000000" netUnrealizedAppr="-9759215.470000000000"/>
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      <mon1Flow redemption="-15648637.270000000000" reinvestment="30404664.710000000000" sales="7315167.060000000000"/>
      <mon2Flow redemption="-8828052.610000000000" reinvestment=".000000000000" sales="5123437.260000000000"/>
      <mon3Flow redemption="-7583343.510000000000" reinvestment=".000000000000" sales="6485056.210000000000"/>


    </fundInfo>
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      <invstOrSec>
        <name>First American Treasury Obliga</name>
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        <title>First American Treasury Obligations Fund</title>
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        <identifiers>
          <isin value="US31846V3289"/>
          <ticker value="FXFXX"/>
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        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>160681038.680000000000</valUSD>
        <pctVal>34.3671363387</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Invesco QQQ Trust Series 1</name>
        <lei>549300VY6FEJBCIMET58</lei>
        <title>Invesco QQQ Trust Series 1</title>
        <cusip>46090E103</cusip>
        <identifiers>
          <isin value="US46090E1038"/>
          <ticker value="QQQ"/>
        </identifiers>
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        <valUSD>49486877.000000000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>iShares US Aerospace &amp; Defense</name>
        <lei>549300BI35CWQ4Q8FM41</lei>
        <title>iShares US Aerospace &amp; Defense ETF</title>
        <cusip>464288760</cusip>
        <identifiers>
          <isin value="US4642887602"/>
          <ticker value="ITA"/>
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        <balance>215300.000000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>24697063.000000000000</valUSD>
        <pctVal>5.2823117044</pctVal>
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        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SPDR S&amp;P 500 ETF Trust</name>
        <lei>549300NZAMSJ8FXPQQ63</lei>
        <title>SPDR S&amp;P 500 ETF Trust</title>
        <cusip>78462F103</cusip>
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          <isin value="US78462F1030"/>
          <ticker value="SPY"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SPDR EURO STOXX 50 ETF</name>
        <lei>549300FS6B2JRJXYB418</lei>
        <title>SPDR EURO STOXX 50 ETF</title>
        <cusip>78463X202</cusip>
        <identifiers>
          <isin value="US78463X2027"/>
          <ticker value="FEZ"/>
        </identifiers>
        <balance>545400.000000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23370390.000000000000</valUSD>
        <pctVal>4.9985573034</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vanguard Growth ETF</name>
        <lei>N/A</lei>
        <title>Vanguard Growth ETF</title>
        <cusip>922908736</cusip>
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          <isin value="US9229087369"/>
          <ticker value="VUG"/>
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        <balance>281887.000000000000</balance>
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        <curCd>USD</curCd>
        <valUSD>65366776.430000000000</valUSD>
        <pctVal>13.9809210598</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vanguard Value ETF</name>
        <lei>N/A</lei>
        <title>Vanguard Value ETF</title>
        <cusip>922908744</cusip>
        <identifiers>
          <isin value="US9229087443"/>
          <ticker value="VTV"/>
        </identifiers>
        <balance>666298.000000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>93021863.780000000000</valUSD>
        <pctVal>19.8959074529</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="The monthly total returns shown in B.5.a do not reflect the deduction of sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2023-05-01</ncom:dateSigned>
      <ncom:nameOfApplicant>North Square Investments Trust</ncom:nameOfApplicant>
      <ncom:signature>/s/ Alan E. Molotsky</ncom:signature>
      <ncom:signerName>Alan E. Molotsky</ncom:signerName>
      <ncom:title>Secretary and Treasurer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
