<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0001750821</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000063487</seriesId>
        <classId>C000205683</classId>
        <classId>C000205681</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>North Square Investments Trust</regName>
      <regFileNumber>811-23373</regFileNumber>
      <regCik>0001750821</regCik>
      <regLei>549300K2CKCXH4E67T58</regLei>
      <regStreet1>10 South LaSalle Street</regStreet1>
      <regStreet2>Suite 1925</regStreet2>
      <regCity>Chicago</regCity>
      <regStateConditional regCountry="US" regState="US-IL"/>
      <regZipOrPostalCode>60603</regZipOrPostalCode>
      <regPhone>3128572160</regPhone>
      <seriesName>North Square Multi Strategy Fund </seriesName>
      <seriesId>S000063487</seriesId>
      <seriesLei>5493001OZ4NHYY86GK88</seriesLei>
      <repPdEnd>2022-05-31</repPdEnd>
      <repPdDate>2021-11-30</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>56437771.170000000000</totAssets>
      <totLiabs>288387.480000000000</totLiabs>
      <netAssets>56149383.690000000000</netAssets>
      <assetsAttrMiscSec>0.000000000000</assetsAttrMiscSec>
      <assetsInvested>0.000000000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.000000000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.000000000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.000000000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.000000000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.000000000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.000000000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.000000000000</amtPayAftOneYrOther>
      <delayDeliv>0.000000000000</delayDeliv>
      <standByCommit>0.000000000000</standByCommit>
      <liquidPref>0.000000000000</liquidPref>
      <cshNotRptdInCorD>5813.860000000000</cshNotRptdInCorD>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000205681" rtn1="-4.580000000000" rtn2="5.810000000000" rtn3="-1.610000000000"/>
          <monthlyTotReturn classId="C000205683" rtn1="-4.560000000000" rtn2="5.830000000000" rtn3="-1.590000000000"/>
        </monthlyTotReturns>
        <othMon1 netRealizedGain="249868.240000000000" netUnrealizedAppr="-2931071.980000000000"/>
        <othMon2 netRealizedGain="2067119.230000000000" netUnrealizedAppr="1110507.230000000000"/>
        <othMon3 netRealizedGain="392810.050000000000" netUnrealizedAppr="-1278863.020000000000"/>
      </returnInfo>
      <mon1Flow redemption="-784753.180000000000" reinvestment=".000000000000" sales="246103.850000000000"/>
      <mon2Flow redemption="-1744936.590000000000" reinvestment=".000000000000" sales="973197.040000000000"/>
      <mon3Flow redemption="-606112.660000000000" reinvestment=".000000000000" sales="124430.640000000000"/>


    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>AdvisorShares North Square McK</name>
        <lei>549300YKE0FBCHCMFG06</lei>
        <title>AdvisorShares North Square McKee ESG Core Bond ETF</title>
        <cusip>00768Y834</cusip>
        <identifiers>
          <isin value="US00768Y8342"/>
          <ticker value="MENV"/>
        </identifiers>
        <balance>35000.000000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>900900.000000000000</valUSD>
        <pctVal>1.6044699706</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>First American Treasury Obliga</name>
        <lei>N/A</lei>
        <title>First American Treasury Obligations Fund</title>
        <cusip>31846V328</cusip>
        <identifiers>
          <isin value="US31846V3289"/>
          <ticker value="FXFXX"/>
        </identifiers>
        <balance>314653.770000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>314653.770000000000</valUSD>
        <pctVal>0.5603868633</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square All Cap Growth Fu</name>
        <lei>5493002SJPUDOVV82U09</lei>
        <title>North Square All Cap Growth Fund</title>
        <cusip>66263L601</cusip>
        <identifiers>
          <isin value="US66263L6011"/>
          <ticker value="ODGIX"/>
        </identifiers>
        <balance>431705.883000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10308791.120000000000</valUSD>
        <pctVal>18.3595801815</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square McKee Bond</name>
        <lei>549300PHHMXSPZQUPF03</lei>
        <title>North Square McKee Bond</title>
        <cusip>66263L759</cusip>
        <identifiers>
          <isin value="US66263L7597"/>
          <ticker value="NMKBX"/>
        </identifiers>
        <balance>150993.108000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1485304.100000000000</valUSD>
        <pctVal>2.6452723118</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square Altrinsic Interna</name>
        <lei>549300UI6YXXFTEM2R11</lei>
        <title>North Square Altrinsic International Equity Fund</title>
        <cusip>66263L767</cusip>
        <identifiers>
          <isin value="US66263L7670"/>
          <ticker value="NSIVX"/>
        </identifiers>
        <balance>100109.030000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1021562.600000000000</valUSD>
        <pctVal>1.8193656508</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square Advisory Research</name>
        <lei>549300TVPQVYWSMZGP04</lei>
        <title>North Square Advisory Research All Cap Value Fund</title>
        <cusip>66263L775</cusip>
        <identifiers>
          <isin value="US66263L7753"/>
          <ticker value="ADVGX"/>
        </identifiers>
        <balance>559060.604000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6603512.040000000000</valUSD>
        <pctVal>11.7606135741</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square Strategic Income</name>
        <lei>549300CK62QE77H6G155</lei>
        <title>North Square Strategic Income Fund</title>
        <cusip>66263L791</cusip>
        <identifiers>
          <isin value="US66263L7910"/>
          <ticker value="ADVNX"/>
        </identifiers>
        <balance>221842.008000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2221326.210000000000</valUSD>
        <pctVal>3.9561007869</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square Dynamic Small Cap</name>
        <lei>549300UFTW8Q6ZS1LI66</lei>
        <title>North Square Dynamic Small Cap Fund</title>
        <cusip>66263L825</cusip>
        <identifiers>
          <isin value="US66263L8256"/>
          <ticker value="ORSIX"/>
        </identifiers>
        <balance>903447.426000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>16981468.850000000000</valUSD>
        <pctVal>30.2433753214</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>North Square Oak Ridge Dividen</name>
        <lei>549300CG4Z7YIUY16D47</lei>
        <title>North Square Oak Ridge Dividend Growth Fund</title>
        <cusip>66263L882</cusip>
        <identifiers>
          <isin value="US66263L8827"/>
          <ticker value="ORDNX"/>
        </identifiers>
        <balance>579780.011000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>14367180.580000000000</valUSD>
        <pctVal>25.5874234690</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Wavelength Interest Rate Neutr</name>
        <lei>549300P8Q6IFOHV2AT44</lei>
        <title>Wavelength Interest Rate Neutral Fund</title>
        <cusip>90386H883</cusip>
        <identifiers>
          <isin value="US90386H8833"/>
          <ticker value="WAVLX"/>
        </identifiers>
        <balance>106808.632000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1172758.780000000000</valUSD>
        <pctVal>2.0886405209</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vanguard Value ETF</name>
        <lei>N/A</lei>
        <title>Vanguard Value ETF</title>
        <cusip>922908744</cusip>
        <identifiers>
          <isin value="US9229087443"/>
          <ticker value="VTV"/>
        </identifiers>
        <balance>7285.000000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1008244.000000000000</valUSD>
        <pctVal>1.7956457110</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="The monthly total returns shown in B.5.a do not reflect the  deduction of sales loads or redemption fees" noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2022-01-20</ncom:dateSigned>
      <ncom:nameOfApplicant>North Square Investments Trust</ncom:nameOfApplicant>
      <ncom:signature>/s/ David Gaspar</ncom:signature>
      <ncom:signerName>David Gaspar</ncom:signerName>
      <ncom:title>Senior Managing Director</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
