Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Cash flows from operating activities:
Net loss	$ (129,474)	$ (96,655)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense	393	377
Loss on disposal of equipment	9	111
Non-cash lease expense	1,150	1,297
Non-cash interest income on marketable securities	(8,175)	(5,524)
Stock-based compensation expense, including employee stock purchase plan expense	22,582	17,256
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(429)	694
Other assets and long-term deposits	(2,957)	(5,324)
Accounts payable	2,510	2,324
Other current liabilities	11,202	2,948
Operating lease liabilities	(1,162)	(1,231)
Net cash used in operating activities	(104,351)	(83,727)
Cash flows from investing activities:
Maturities of marketable securities	301,592	250,760
Purchases of marketable securities	(394,959)	(255,625)
Purchase of equipment	(159)
Disposal of fixed assets		14
Net cash used in investing activities	(93,526)	(4,851)
Cash flows from financing activities:
Proceeds from equity private placement, net of issuance costs of $6,498	243,501	129,736
Proceeds from at-the-market offering, net of issuance costs of $166	22,787
Proceeds from exercise of stock options	1,671	2,629
Proceeds from issuance of common stock under the ESPP plan	859	1,050
Net cash provided by financing activities	268,818	133,415
Net increase in cash and cash equivalents	70,941	44,837
Cash and cash equivalents at beginning of period	68,539	23,702
Cash and cash equivalents at end of period	139,480	$ 68,539
Supplemental disclosure of non-cash investing and financing activities:
Issuance costs for equity private placement not paid in cash by the end of period	6,500
Exchange common stock shares for pre-funded warrants	31,054
Research and development project deposit applied against final study invoices	748
System implementation cost included in other current liabilities	$ (337)