Subsequent Events - Additional Information (Details) $ / shares in Units, $ in Millions				12 Months Ended
	Mar. 10, 2023 USD ($) shares	Mar. 06, 2023 USD ($) shares	Feb. 09, 2021 £ / shares shares	Dec. 31, 2022 £ / shares	Jan. 01, 2025 $ / shares	Dec. 31, 2024 $ / shares	Mar. 10, 2023 £ / shares shares	Mar. 10, 2023 $ / shares shares	Mar. 06, 2023 £ / shares shares	Mar. 06, 2023 $ / shares shares	Dec. 31, 2021 £ / shares
Subsequent Event [Line Items]
Ordinary shares, nominal value | £ / shares				£ 0.10							£ 0.10
Private Placement | Securities Purchase Agreement
Subsequent Event [Line Items]
Sale of voting and non-voting ordinary shares, net of issuance costs, Shares			20,900,321
Ordinary shares, nominal value | £ / shares			£ 0.10
Private Placement | Securities Purchase Agreement | Non-voting Ordinary Shares
Subsequent Event [Line Items]
Sale of voting and non-voting ordinary shares, net of issuance costs, Shares			3,215,434
Ordinary shares, nominal value | £ / shares			£ 0.10
Scenario Forecast | 2023 Private Placement
Subsequent Event [Line Items]
Warrants to purchase price per share | $ / shares					$ 0.95	$ 1.10
Warrants exercisable term						30 days
Subsequent Event
Subsequent Event [Line Items]
Ratio change, reverse stock split description	On February 10, 2023, the Company announced that the Company's Board of Directors approved a change to the ratio of the Company's ADSs to ordinary shares (the "ADS Ratio") from the previous ADS Ratio of one ADS to one ordinary share to a new ADS Ratio of one ADS to ten ordinary shares. The ratio change became effective on March 10, 2023. The change in the ADS Ratio had the same effect as a one-for-ten reverse ADS split and is intended to enable the Company to regain compliance with the Nasdaq minimum bid price requirement. As all financial statement and disclosure information is presented in ordinary share amounts, not ADSs, there was no impact to the consolidated financial statements and footnote disclosures.
Sale of voting and non-voting ordinary shares, net of issuance costs, Shares	56,666,900
Ordinary shares, nominal value | £ / shares							£ 0.10
Warrants to purchase ordinary shares							62,333,590	62,333,590
Warrants to purchase price per share | $ / shares								$ 6.00
Subsequent Event | 2023 Private Placement
Subsequent Event [Line Items]
Gross proceeds of offering | $	$ 34.0
Shares sold in fixed combinaton of warrants as units		The 2023 Private Placement consists of two closings. The Company agreed to sell and issue in the initial closing of the 2023 Private Placement (i) 56,666,900 Shares and (ii) Warrants to purchase an aggregate of 62,333,590 Shares, at a purchase price of $6.00 per unit, where each unit consists of ten (10) Shares and an accompanying Warrant to purchase eleven (11) Shares. The initial closing of the 2023 Private Placement occurred on March 10, 2023. The Company received gross proceeds of approximately $34.0 million from the initial closing of the 2023 Private Placement, before deducting fees to the placement agent and other offering expenses payable by the Company.
Warrants expiration, description		The Warrants will expire at the conclusion of the 30-day exercise period or, if the Vesting Event does not occur, March 10, 2026.
Subsequent Event | 2023 Private Placement | Securities Purchase Agreement
Subsequent Event [Line Items]
Sale of voting and non-voting ordinary shares, net of issuance costs, Shares		99,166,900
Ordinary shares, nominal value | £ / shares									£ 0.10
Warrants to purchase ordinary shares									109,083,590	109,083,590
Subsequent Event | 2023 Private Placement | Securities Purchase Agreement | Non-voting Ordinary Shares
Subsequent Event [Line Items]
Ordinary shares, nominal value | £ / shares									£ 0.10
Subsequent Event | Initial Closing | 2023 Private Placement | Securities Purchase Agreement
Subsequent Event [Line Items]
Sale of voting and non-voting ordinary shares, net of issuance costs, Shares	56,666,900
Warrants to purchase ordinary shares							62,333,590	62,333,590
Warrants to purchase price per share | $ / shares								$ 6.00
Gross proceeds of offering | $	$ 34.0
Subsequent Event | Second Closing | 2023 Private Placement | Securities Purchase Agreement
Subsequent Event [Line Items]
Sale of voting and non-voting ordinary shares, net of issuance costs, Shares		42,500,000
Warrants to purchase ordinary shares									46,750,000	46,750,000
Warrants to purchase price per share | $ / shares										$ 8.00
Gross proceeds of offering | $		$ 34.0
ADS
Subsequent Event [Line Items]
Current ADS ratio				1
ADS | Subsequent Event
Subsequent Event [Line Items]
Current ADS ratio	0.1