Product Revenue, Net - Schedule of Net Revenue by Product (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Disaggregation of Revenue [Line Items]
Total revenues	$ 22,655	$ 1,675
Libmeldy
Disaggregation of Revenue [Line Items]
Total revenues	18,796
Strimvelis
Disaggregation of Revenue [Line Items]
Total revenues	1,814	700
Product
Disaggregation of Revenue [Line Items]
Total revenues	$ 20,610	$ 700