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Summary of Significant Accounting Policies - Securities Excluded in the Computation of Diluted Net Loss Per Ordinary Share (Details) - shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Common shares attributable to anti-dilutive shares 15,330,158 14,555,689
Share options    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Common shares attributable to anti-dilutive shares 13,076,959 14,042,781
Unvested Restricted Incentive Shares    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Common shares attributable to anti-dilutive shares 2,253,199 512,908