Summary of Significant Accounting Policies - Summary of Amounts recognized to Offset Research and Development Expense (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Summary Of Significant Accounting Policies [Line Items]
Receipt of credit claims	$ (2,049)	$ (2,232)
Foreign currency translation	(24,300)	(1,200)
United Kingdom | Research and Development Expense
Summary Of Significant Accounting Policies [Line Items]
Balance at beginning of period	30,723	17,344
Recognition of credit claims as offset to research and development expense	8,243	13,920
Receipt of credit claims	(30,811)
Foreign currency translation	(2,213)	(541)
Balance at end of period	$ 5,942	$ 30,723