Summary of Significant Accounting Policies - Schedule of Changes in Loss Provision (Details) - Strimvelis - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Asset Acquisition [Line Items]
Balance at beginning of period	$ 3,419	$ 4,482
Amortization of loss provision	(274)	(1,037)
Foreign currency translation	(326)	(26)
Balance at end of period	$ 2,819	$ 3,419