Product Revenue, Net (Tables)

12 Months Ended

Dec. 31, 2022

Revenue from Contract with Customer [Abstract]

Disaggregated Product Revenue

The following table presents the Company's net revenue by product (in thousands):

	Year Ended December 31,
	2022		2021
Libmeldy	$	18,796	$	—
Strimvelis		1,814		700
Total	$	20,610	$	700

Summary of Net Product Revenue of Libmeldy by Geography

Net product revenue of Libmeldy by geography consisted of the following and is attributable to individual countries based on the location of the customer as of December 31, 2022 (in thousands):

	Year ended December 31, 2022
United Kingdom	$	6,322
Italy		5,544
France		3,883
Germany		3,047
Total Libmeldy revenue, net	$	18,796

Summary of Activity of Product Revenue Allowance and Reserve Categories

Activity in each of the product revenue allowance and reserve categories for Libmeldy is summarized as follows (in thousands):

	Trade Discounts and Allowances			Government rebates		Total
Balance as of December 31, 2021	$	—		$	—	$	—
Provision Related to sales in the current year		4,573			2,300		6,873
Credits and payments made during the period		(183	)		—		(183	)
Balance as of December 31, 2022	$	4,390		$	2,300	$	6,690

Summary as Components of Balance Sheets

The total reserves described above are summarized as components of the Company's consolidated balance sheets as follows (in thousands):

	December 31, 2022
Reduction of accounts receivable, net	$	4,390
Component of accrued expenses and other current liabilities		2,300
Balance as of December 31, 2022	$	6,690