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Document and Entity Information - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2022
Mar. 10, 2023
Jun. 30, 2022
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2022    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Entity Registrant Name ORCHARD THERAPEUTICS PLC    
Current Fiscal Year End Date --12-31    
Entity Central Index Key 0001748907    
Entity Filer Category Non-accelerated Filer    
Entity Well-known Seasoned Issuer No    
Entity Small Business true    
Entity Common Stock, Shares Outstanding   183,984,499  
Entity Public Float     $ 74
Entity Shell Company false    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Incorporation, State or Country Code X0    
Entity Address, Address Line One 245 Hammersmith Road    
Entity Address, City or Town London    
Entity Address, Postal Zip Code W6 8PW    
City Area Code 44    
Local Phone Number (0) 203 808-8286    
Document Annual Report true    
Document Transition Report false    
Entity File Number 001-38722    
Entity Emerging Growth Company false    
Entity Tax Identification Number 00-0000000    
Entity Address, Country GB    
ICFR Auditor Attestation Flag false    
Auditor Firm ID 238    
Title of 12(b) Security American Depositary Shares, each representing one ordinary share, nominal value £0.10 per share    
Trading Symbol ORTX    
Security Exchange Name NASDAQ    
Auditor Name PricewaterhouseCoopers LLP    
Auditor Location Boston, Massachusetts    
Documents Incorporated by Reference

Portions of the Registrant’s definitive proxy statement for its 2023 Annual General Meeting are incorporated by reference into Part III of this Annual Report on Form 10-K where indicated.