X0206 3 2018-07-26 0 0000318154 AMGEN INC AMGN 0001748434 REESE DAVID M ONE AMGEN CENTER DRIVE THOUSAND OAKS 1 EVP, Research and Development Common Stock 17732 D Nqso (Right to Buy) 58.43 2012-04-26 2020-04-26 Common Stock 1480 D Nqso (Right to Buy) 54.69 2013-04-25 2021-04-25 Common Stock 2300 D Nqso (Right to Buy) 156.35 2018-05-03 2026-05-03 Common Stock 8711 D Nqso (Right to Buy) 162.60 2019-05-01 2027-05-01 Common Stock 8714 D Nqso (Right to Buy) 177.46 2020-04-27 2028-04-27 Common Stock 7807 D These shares include the following Restricted Stock Units (RSUs) granted under the Company's equity plans: 313 RSUs which vest fully in one installment on 1/30/2019; 686 RSUs which vest in installments of 338 and 348 on 5/3/2019 and 5/3/2020, respectively; 4,920 RSUs which vest in installments of 1,623, 1,624 and 1,673 on 5/1/2019, 5/1/2020 and 5/1/2021, respectively; 984 RSUs which vest in installments of 324, 325 and 335 on 5/1/2019, 5/1/2020 and 5/1/2021, respectively; and 1,014 RSUs which vest in installments of 334, 335 and 345 on 4/27/2020, 4/27/2021 and 4/27/2022, respectively. These shares include 282 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited to the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount. These options were fully exercisable on 4/26/2014. These options were fully exercisable on 4/25/2015. 2,874 of these options have vested and the remainder are exercisable in two installments of 2,875 and 2,962 on 5/3/2019 and 5/3/2020, respectively. These stock options are exercisable in three annual installments of 33%, 33% and 34% on 5/1/2019, 5/1/2020 and 5/1/2021, respectively. These stock options are exercisable in three annual installments of 33%, 33% and 34% on 4/27/2020, 4/27/2021 and 4/27/2022, respectively. /s/ David M. Reese 2018-08-02