X0206 3 2022-11-28 0 0001434647 KEMPHARM, INC KMPH 0001748265 Posner Christopher C/O KEMPHARM, INC. 1180 CELEBRATION BOULEVARD, SUITE 103 CELEBRATION FL 34747 1 Stock Option (right to buy) 4.6700 2032-11-27 Common Stock 22500 D Grant to the Reporting Person of a stock option under the Issuer's Amended and Restated 2014 Equity Incentive Plan (the "Plan"). 33.33% of the total shares subject to the option vest in equal annual installments beginning on November 28, 2023 through November 28, 2025, provided that at the relevant vesting dates such optionee's directorial relationship has not been terminated as defined in and as determined under the Plan. All shares underlying the option will vest in full and become immediately exercisable upon a change of control of the Issuer. The option expires ten years after the date of grant. Exhibit List: Exhibit 24 - Power of Attorney. /s/ Timothy J. Sangiovanni, Attorney-in-Fact for Christopher A. Posner 2022-11-30