Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Deferred tax assets:
Net operating losses	$ 130,017	$ 94,882
Research and development credits	43,032	37,740
Accrued expenses	1,168	1,862
Other	779	757
Capitalized research and development	46,789	55,291
Lease liability	6,118	6,300
Stock based compensation	6,983	7,722
Total deferred tax assets	234,886	204,554
Deferred tax liabilities:
Prepaid expenses	(300)	(331)
Right of use asset	(5,038)	(5,725)
Total deferred tax liabilities	(5,338)	(6,056)
Valuation allowance	229,548	198,498	$ 153,941
Net deferred taxes	$ 0	$ 0