Property and Equipment, net -Schedule of Property and Equipment Net (Details) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	$ 13,809	$ 16,332
Less: Accumulated depreciation	(10,869)	(10,807)
Total property and equipment, net	2,940	5,525
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	8,563	10,988
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	2,156	2,118
Furniture and Fixture
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	1,832	1,775
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	1,105	1,105
Construction-in-progress
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	$ 153	$ 346