Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Current assets
Cash and cash equivalents	$ 45,445	$ 71,188
Short-term investments	145,499	284,536
Prepaid expenses and other current assets (Note 5)	4,464	6,540
Property and equipment held for sale (Note 4)	1,040	0
Total current assets	196,448	362,264
Property and equipment, net (Note 4)	2,940	5,525
Operating lease right-of-use assets	23,966	27,243
Restricted cash	1,482	1,482
Other non-current assets	392	435
Total assets	225,228	396,949
Current liabilities
Accounts payable	480	5,960
Accrued research and development	4,804	14,363
Accrued liabilities (Note 6)	9,634	12,353
Lease liabilities, current	1,447	542
Total current liabilities	16,365	33,218
Lease liabilities, non-current	27,658	29,439
Long-term debt (Note 7)	0	30,211
Total liabilities	44,023	92,868
Commitments and Contingencies (Note 14)
Stockholders’ equity
Preferred stock, $0.0001 par value 10,000,000 shares authorized at December 31, 2025 and 2024, none issued or outstanding at December 31, 2025 and 2024	0	0
Common stock, $0.0001 par value; 300,000,000 shares authorized at December 31, 2025 and 2024; and 61,449,290 and 60,860,838 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively;	6	6
Additional paid-in capital	1,040,610	1,013,806
Accumulated deficit	(859,396)	(710,052)
Accumulated other comprehensive (loss) gain	(15)	321
Total stockholders’ equity	181,205	304,081
Total liabilities and stockholders’ equity	$ 225,228	$ 396,949