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Segments - Schedule of Segment Reporting Expenses (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Sep. 30, 2025
Sep. 30, 2024
Operating expenses:                
Segment loss $ 28,269     $ 62,014     $ 132,796 $ 175,045
Reconciliation of segment loss                
Interest and other (income) expense, net (2,783)     (5,128)     (9,452) (16,663)
Interest expense 815     877     2,423 2,190
Net loss 26,301 $ 43,300 $ 56,166 57,763 $ 55,854 $ 46,955 125,767 160,572
Reportable Segment                
Operating expenses:                
Bexotegrast - clinical trial and third party contracting costs 4,526     26,713     39,474 70,290
Employee-related expenses - research and development (excluding stock-based compensation) 5,180     8,778     26,010 26,297
General and administrative costs (excluding stock-based compensation) 6,261     8,963     25,497 26,089
Other segment items 12,302     17,560     41,815 52,369
Segment loss 28,269     62,014     132,796 175,045
Reconciliation of segment loss                
Interest and other (income) expense, net (2,783)     (5,128)     (9,452) (16,663)
Interest expense 815     877     2,423 2,190
Net loss $ 26,301     $ 57,763     $ 125,767 $ 160,572