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Equity Incentive Plans and Stock-Based Compensation - Schedule of Option Activity Under the 2015 Plan and 2020 Plan (Details) - Incentive Stock Options and Nonqualified Stock Options - 2015 Equity and 2020 Incentive Plan - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2025
Dec. 31, 2024
Number of Options    
Outstanding, beginning balance (in shares) 8,300,804  
Granted (in shares) 2,271,680  
Exercised (in shares) (4,921)  
Forfeited (in shares) (2,479,046)  
Outstanding, ending balance (in shares) 8,088,517 8,300,804
Number of options, exercisable (in shares) 5,108,451  
Number of options, vested and expected to vest (in shares) 8,088,517  
Weighted- Average Exercise Price per Share    
Outstanding, beginning balance (USD per share) $ 17.23  
Granted (USD per share) 9.68  
Exercised (USD per share) 12.18  
Forfeited (USD per share) 16.43  
Outstanding, ending balance (USD per share) 15.36 $ 17.23
Weighted- average exercise price per share, exercisable (USD per share) 16.29  
Weighted- average exercise price per share, vested and expected to vest (USD per share) $ 15.36  
Weighted- Average Remaining Contractual Term (in Years)    
Weighted- average remaining contractual term (in years), outstanding 6 years 11 months 26 days 7 years 5 months 26 days
Weighted- average remaining contractual term (in years), exercisable 5 years 11 months 19 days  
Weighted- average remaining contractual term (in years), vested and expected to vest 6 years 11 months 26 days  
Aggregate intrinsic value, outstanding balance $ 0 $ 13,769
Aggregate intrinsic value, exercisable 0  
Aggregate intrinsic value, vested and expected to vest $ 0