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Equity Incentive Plans and Stock-Based Compensation - Schedule of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for Stock Option Awards (Details) - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected volatility, maximum 208.00%   208.00% 63.92%
Risk-free interest rate, maximum   5.27%   5.27%
Incentive Stock Options and Nonqualified Stock Options | 2015 and 2020 Equity Incentive Plans and 2020 Inducement Plan        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected volatility 0.00%      
Expected volatility, minimum   85.14% 86.82% 85.14%
Expected volatility, maximum   85.74% 89.30% 86.46%
Risk-free interest rate 0.00%      
Risk-free interest rate, minimum   3.45% 3.98% 3.45%
Risk-free interest rate, maximum   4.20% 4.45% 4.60%
Expected dividend 0.00% 0.00% 0.00% 0.00%
Underlying common stock fair value $ 0      
Incentive Stock Options and Nonqualified Stock Options | 2015 and 2020 Equity Incentive Plans and 2020 Inducement Plan | Minimum        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected term (in years)   6 years 3 days 5 years 4 months 2 days 5 years 3 months 21 days
Underlying common stock fair value   $ 11.09 $ 1.37 $ 11.09
Incentive Stock Options and Nonqualified Stock Options | 2015 and 2020 Equity Incentive Plans and 2020 Inducement Plan | Maximum        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected term (in years)   6 years 25 days 6 years 29 days 6 years 29 days
Underlying common stock fair value   $ 13.23 $ 12.63 $ 17.44